Human origin recognition complex

E.-M. Ladenburger, C. Keller, and R. Knippers, Identification of a binding region for human origin recognition complex proteins 1 and 2 that coincides with an origin of DNA rephcation. Mol. Cell. Biol. 22, 1036-1048 (2002). 

C. Keller, E.-M. Ladenburger, M. Kremer, and R. Knippers, The origin recognition complex marks a replication origin in the human TOPI gene promoter. J. Biol. Chem. 277,31430-31440 (2002). 

ENVIRONMENTAL POLLUTION deals with the modification of the chemical environment of the earth by human activity its study encompasses the sources, distribution, and effects of pollutants, that is, chemical substances introduced into the environment in locations and/or at levels not observed in the absence of human intervention. Environmental pollution as a discipline originates in the recognition that the terrestrial soil-hydrosphere-atmosphere-biosphere system is an interlinked set of reservoirs with complex connective pathways, so that modification of chemical conditions in one region can propagate in unintended ways into others, producing unexpected and undesirable effects. 

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