Permissible cells

The duration of expression of transferred genes can vary, and is usually transient Infection of permissive cells with wild-type adenovirus usually results in cell lysis Adenoviruses display a broad selectivity in the cell types they can infect... 

Nisole S, Krust B, Hovanessian AG (2002a) Anchorage of HIV on Permissive Cells Leads to Coaggregation of Viral Particles with Surface Nucleolin at Membrane Raft Microdomains. Exp Cell Res... 

The reproductive cycle of viruses may take hours or days. The infection of cells does not guarantee the production of viral progeny, which may be productive, restricted, aborted, or latent. A productive infection occurs in permissible cells and results in infectious viral particles. An abortive infection may occur in two circumstances firstly, although the cell is sensitive to infection, it is not necessarily permissive, allowing the expression of only a few viral genes. The second circumstance is when a sensitive cell, permissive or not, is infected by defective viruses that do not have all the necessary viral genes for their replication. Furthermore, the cells can be temporarily permissible. In this case, the viral particles may remain in the cells until they become permissive or else some viral particles may be... 

Insect cell lines present different susceptibilities to virus replication. A cell line is called permissive when it can support full virus replication and all stages of viral cycle are completed, leading to polyhedra production and lysis of the host cell. Semi-permissive cell lines allow partial virus replication, possibly due to a restriction at a particular viral cycle stage (Bilimoria et al., 1992). Abortive cell lines are those in which the resulting virus may have a cytopathic effect, but there are no infective particles produced (Carpenter and Bilimoria, 1983 Liu and Bilimoria, 1990). 

Temperature-sensitive variants of the BHK21 PyY cells have been selected, which at the non-permissive temperature are unable to make T-antigen, and the host cell reverts to its non-transformed character (Dulbecco, 1969). Thus the expression of viral functions depends on the conditions of culture, and often virulent virus may be rescued from non-permissive cells by fusion with uninfected permissive cells (Green, 1970). A similar in vitro rescue can be used... 

Herpes simplex virus type 1 (HSV-1) is a double-stranded DNA virus that has a genome size of 152 Kb, and it encodes at least 84 proteins. Binding and entry of HSV-1 into permissive cells is mediated by viral proteins binding to cellular... 

When the virus was used to infect a known, fully permissive cell line from Spodoptera frugiperdaf both genes were expressed. CAT activity was detected early in the infection at about six hours, a not surprising result since the RSV LTR contains an RNA polymerase II promoter and this enzymatic activity, pre-existing in the cell, should be amongst the first to act on the viral chromosome. Late in the infection, at the time that the polyhedrin promoter is known to become active, P-galactosidase activity was detected. 

Sun L.-Q., Warrilow D., Wang L., Witherington C., Macpherson J., Symonds G. (1994) Ribozyme-mediated suppression of Moloney murine leukemia virus and human immunodeficiency virus type I replication in permissive cell lines. Proc Natl. Acad. Sci. USA 91 9715. 

Similar results to the above have been found in other systems. Hybrids between SV-40 permissive and non-permissive cells (29, 50) were resistant to challenge by SV-40. However, the reason for this is probably totally different from the one involving mengovirus in MDBK, since the presence of an integration region on the chromosome (5I ) allowed for expression of late viral function. 

Hybrids between human and mouse cell have also been used in mapping the polio receptor site (52). Hamster-mouse hybrids, and human-mouse hybrids are susceptible to polyoma virus (53) as long as the parental mouse chromosomes (permissive cell line) were... 

The maximum permissible cell volume (Vopt) in any type of HPLC detector is approximated by ... 

General Features of the Response of Permissive Cells to Adenovirus Infection... 

Some of the pioneering studies of adenovirus infection performed during the decade following the virus discovery elucidated the general properties of the response of permissive cells to adenovirus infection as descriptions in morphological terms were rapidly succeeded by investigations of alterations in macromolecular synthesis. 

Adenovirus infection of rapidly growing permissive cells, for example, HeLa cells in suspension culture, leads to the cessation of cell division in 10-12 hr (Green and Daesch, 1961). Nevertheless, such infected cells do continue macromolecular synthesis and have been reported to contain twice the mass, compared to uninfected cells, of DNA and protein by 32 hr after infection (Green and Daesch, 1961 ... 

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