Wolf studies

Phenylazide was first synthesized by Greiss in 1864. In 1912, Wolf studied the pyrolysis of phenyl azide in aniline. The product of this reaction, azepine (27), was identified by Huisgen and co-worker in 1958. Eight years later. Doering and Odum demonstrated that azepine (27) is formed upon photolysis of phenylazide in diethylamine and in 1977 Carroll et al. ° discovered the formation of 28 upon photolysis of phenyl azide in the presence of ethanethiol. 

In the early 1940s, Cornell University professors Harold Wolff and Stewart Wolf studied the response of the human stomach to a range of emotions predpitated by stressful situations in everyday life. These interests, which were focused on peptic ulceration, were facilitated by the availability of Tom (bottom), a patient with a large gastric fistula (center left). The investigations of Tom became a model for the study of human physiology with the voluntary cooperation of a patient and were later detailed in Time magazine. 

Jeger, Wolf and coworkers extensively studied the photochemistry of butadienyloxiranes (81HCA198) and oxiranyl enones (81HCA224). Butadienyloxiranes give both C—O and C—C cleavage (Scheme 13) the paths open to oxiranyl enones have been systematically analyzed... 

S Modi, MI Paine, MI Sutcliffe, L-Y Lian, WU Pnmi-ose, CR Wolfe, GCK Roberts. A model for human cytochrome P450 2d6 based on homology modeling and NMR studies of substrate binding. Biochemistry 35 4540-4550, 1996. 

By these studies half of the ten water molecules predicted by Wolf and Hanlon 159) for the primary shell could be found probably because these correspond to the number of water molecules at fixed positions under the experimental conditions used. In the second layer of water molecules only two water molecules on average were found whereas eight are predicted by Wolf and Hanlon 159). Experimental reasons are probably responsible for these deviations. 

Rheumatoid Arthritis. Figure 1 The development of disability overtime in a group of RA patients studied prior to the early 1990s. FDI = functional disease index where 1 = moderate disability, 2 = more marked disability, 3 = severe disability and 4 = very severe disability (from Wolfe, Cathey (1991) J Rheumatol 18 1298). 

For leading references see S. Wolfe, L. A. LaJohn and D. F. Weaver, Tetrahedron Letters, 25, 2863 (1984) Cor study of a-lithiosulfinyl carbanion initiated oligomerization, see M. Buese and T. E. Hogan-Esch, J. Amer. Chem. Soc., 107,4509 (1985) for a study of a-lithiosulfinyl carbanion alkylation in a cyclic system, see Y. Tamura, J. Uenishi and H. Ishibashi, Chem. Pharm. Bull., 32, 891 and 898 (1984). 

Phase diagram studies of the magnesium-al uminum-zinc system have shown that there exists a ternary phase, which has been given the name A phase or T phase (Egar, 1913 Koster Wolf, 1936 Koster ... 

Gray LE, Ostby J, Wolf C, et al. 1998. The value of mechanistic studies in laboratory animals for the prediction of reproductive effects in wildlife Endocrine effects of mammalian sexual differentiation. Environ Toxicol Chem 17(1) 109-118. 

In another study exposure of water containing NDEA to sunlight caused a raoid decrease in the NDEA concentration (to near zero after 16 h)2Q. Wolfe, et al. 2fi found Ji-nitrosoatrazine to be photolabile in natural water with both denitrosation and dealkylation being identified as decomposition pathways. 

Hess, Ch., Bonn, M., Funk, S. and Wolf, M. (2000) Hot-band exdtation of CO chemisorbed on Ru(OOl) studied with broadband-IR sum-frequency generation. Chem. Phys. Lett., 325, 139—145. 

In Wolf WR, ed. Biological Reference Materials, pp. 109-140. John Wiley Sons New York. Okamoto K and Fuwa K (1985) Certified reference material program at the National Institute for Environmental Studies. Anal Sd 1 206-207. 

Much of the analytical data on the nutrient content of foods is generated using official methods of analysis (e.g. AO AC International). An evaluation of AO AC Methods of Analysis for Nutritional Labelling is available (Sullivan and Carpenter 1993). While these methods have often been studied for a variety of food matrices, applicability over the entire range of food matrices has not been formally studied in most cases. In addition, RMs are not available over the entire range of food matrices (Wolf... 

Drawing on this representation, an approach has been described to systematically describe selection of food products to evaluate the applicability of collaboratively studied methods over a range of food matrices (Wolf and Andrews 1995). A food matrix is described by its location in one of the nine sectors in the triangle. Foods falling within the same sector are chemically similar and thus should behave in a similar analytical manner. This same scheme can be used to select food matrices representing each sector for development of a series of RMs representing all foods. 

Gracia FJ, Guerrero S, Wolf EE, Miller JT, Kropf A. 2005. Kinetics, operando ETIR, and controlled atmosphere EXAFS study of the effect of sulfur on Pt-supported catalysts during CO oxidation. J Catal 233 372-387. 

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